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320-67-2 - 5-Azacytidine, 98% - 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one - Ladakamycin - J64159 - Alfa Aesar

J64159 5-Azacytidine, 98%

Codice CAS
320-67-2
Sinonimi
4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
Ladakamycin

Dimensioni Prezzo ($) Quantità Disponibilità
1g 53,60
5g 214,00
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5-Azacytidine, 98%

MDL
MFCD00006539
EINECS
206-280-2

Proprietà chimiche

Formula
C8H12N4O5
Peso formula
244.2
Modulo
Powder
Punto di fusione
226-232° dec.
Solubilità
Soluble in water.

Applicazioni

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Note

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Letteratura

Siva P. Kumpatla.; Timothy C. Hall. Longevity of 5-azacytidine-mediated gene expression and re-establishment of silencing in transgenic rice. Plant Molecular Biology. 1998, 38, (6), 1113-1122.

Sunil Rangappa.; Chen Fen.; Eng Hin Lee.; Ariff Bongso.; Eugene Sim Kwang Wei. Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. The Annals of Thoracic Surgery. 2003, 75, (3), 775-779.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H340-H350

Harmful if swallowed. May cause genetic defects. May cause cancer.

Dichiarazioni precauzionali: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,890
Beilstein
620461
Codice tariffe armonizzato
2934.99
TSCA
No
RTECS
XZ3017500

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