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50-63-5 - Chloroquine diphosphate salt, 98% - N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt - J64459 - Alfa Aesar

J64459 Chloroquine diphosphate salt, 98%

Codice CAS
50-63-5
Sinonimi
N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt

Dimensioni Prezzo ($) Quantità Disponibilità
25g 52,60
50g 94,60
100g 156,00
250g 309,00
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Chloroquine diphosphate salt, 98%

MDL
MFCD00069852
EINECS
200-055-2

Proprietà chimiche

Formula
C18H26ClN3.2H3PO4
Peso formula
515.87
Modulo
Powder
Punto di fusione
213-216°
Solubilità
Soluble in water

Applicazioni

Chloroquine diphosphate salt is used to study the role of endosomal acidification in cellular processes, such as the signaling of intracellular TLRs. It can be used as DNA intercalator & to dissociate antigen antibody complexes without denaturing red blood cell antigens. Chloroquine showed very high antiviral activity against NiV but very little activity against the other viruses at concentrations lower than 20 µM.

Note

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Letteratura

Maria Cristina Gaudiano.; Eleonora Antoniella.; Paola Bertocchi.; Luisa Valvo. Development and validation of a reversed-phase LC method for analyzing potentially counterfeit antimalarial medicines. Journal of Pharmaceutical and Biomedical Analysis. 2006, 42, (1), 132-135.

Minchinton, R.M.; Waters, A.H. Chloroquine stripping of HLA antigens from neutrophils without removal of neutrophil specific antigens. British Journal of Haematology. 1984, 57, (4), 703-706.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302

Harmful if swallowed.

Dichiarazioni precauzionali: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,2163
Beilstein
4223142
Codice tariffe armonizzato
2933.49
TSCA
No
RTECS
VB2450000

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