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Azadibenzocyclooctyne acid - ADIBO-acid - J64549 - Alfa Aesar

J64549 Azadibenzocyclooctyne acid

Codice CAS
Sinonimi
ADIBO-acid

Dimensioni Prezzo ($) Quantità Disponibilità
25mg 145,00
100mg 374,00
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Azadibenzocyclooctyne acid

MDL
MFCD22380737

Proprietà chimiche

Formula
C21H19NO3
Peso formula
333.38
Modulo
Solid
Solubilità
Soluble in dimethyl sulfoxide and dimethyl formamide.

Applicazioni

Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.

Note

Store in cool place. Incompatible with amines.

Letteratura

Patterson, D. M.; Prescher, J. A. Orthogonal bioorthogonal chemistries. Curr. Opin. Chem. Biol. 2015, 28, 141-149.

Jung, S.; Yi, H. Integrated fabrication-conjugation approaches for biomolecular assembly and protein sensing with hybrid microparticle platforms and biofabrication - A focused minireview. Korean J. Chem. Eng. 2015, 32 (9), 1713-1719.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.99
TSCA
No

Raccomandato

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    (S)-(+)-2-Indolinemethanol, 98+%
  • L06866

    Cumene hydroperoxide, tech. 80%
  • J64128

    Azadibenzocyclooctyne-NHS ester, with 4 carbon linker

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