Autorizzo l’utilizzo di cookies.

Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato

Acetylene-PEG4-maleimide - 3-(N-maleimidyl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propionamide - J64859 - Alfa Aesar

J64859 Acetylene-PEG4-maleimide

Codice CAS
Sinonimi
3-(N-maleimidyl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propionamide

Dimensioni Prezzo ($) Quantità Disponibilità
25mg 103,00
100mg 245,00
500mg 823,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Acetylene-PEG4-maleimide

MDL
MFCD22380740

Proprietà chimiche

Formula
C18H26N2O7
Peso formula
382.41
Modulo
Viscous liquid or solid
Solubilità
Soluble in water.

Applicazioni

Heterobifunctional cross linker enabling the connection of an azide containing compound or biomolecule to one with a thiol. The maleimide group will react preferentially with thiols to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification cysteine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character. A bifunctional linker with sulfhydryl reactive and azide reactive groups. Contains a PEG spacer to increase solubility

Note

Keep container tightly closed. Store away from oxidizing agents.

Letteratura

Hao Jiang.; Tianqing Zheng.; Aime Lopez-Aguilar.; Lei Feng.; Felix Kopp.; Florence L. Marlow.; Peng Wu. Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem. 2014, 25, (4), 698-706.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2925.29
TSCA
No

Raccomandato

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio