Autorizzo l’utilizzo di cookies.

Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato

53-85-0 - 5,6-Dichlorobenzimidazole riboside, 98% - DBR - 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole - J64870 - Alfa Aesar

J64870 5,6-Dichlorobenzimidazole riboside, 98%

Codice CAS
53-85-0
Sinonimi
DBR
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole

Dimensioni Prezzo ($) Quantità Disponibilità
50mg 141,00
100mg 273,00
250mg 562,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

5,6-Dichlorobenzimidazole riboside, 98%

MDL
MFCD00036785

Proprietà chimiche

Formula
C12H12Cl2N2O4
Peso formula
319.14
Modulo
Powder
Solubilità
Soluble in DMSO to 75mMSoluble in dimethyl sulfoxide, hot ethanol, dimethyl formamide, (1:2) dimethyl formamide:Phosphate buffer saline, water, methanol and pyridine. Slightly soluble in aqueous buffers.

Applicazioni

Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

Note

Incompatible with heat and oxidizing agents.

Letteratura

Liu, Y.; He, X.; Sui, Y.; Yu, R.; Xu, G. Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition. FEBS Lett. 2015, 589 (17), 2233-2240.

Bartkowiak, B.; Greenleaf, A. L. Expression, Purification, and Identification of Associated Proteins of the Full-length hCDK12/CyclinK Complex. J. Biol. Chem. 2015, 290 (3), 1786-1795.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
39123
Codice tariffe armonizzato
2938.90
TSCA
No
RTECS
DD7310000

Raccomandato

  • M10080

    CSM-LEU (POWDER)
  • A14757

    1-Formylpiperazine, 90+%
  • H63368

    1-Methyl-4-(2-nitrophenyl)piperazine, 97%
  • J60151

    5-Bromo-4-chloro-3-indolyl-alpha-D-galactoside
  • H62579

    cis-3-(Benzyloxymethyl)cyclobutanol, 97%

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio