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Orexin B, human - Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 - J65110 - Alfa Aesar

J65110 Orexin B, human

Codice CAS
Sinonimi
Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Dimensioni Prezzo ($) Quantità Disponibilità
0.5mg 155,00
1mg 270,00
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Orexin B, human

MDL
MFCD01635373

Proprietà chimiche

Formula
C123H212N44O35S
Peso formula
2899.33
Modulo
Lyophilized powder
Solubilità
Soluble in water at 1mg/ml

Applicazioni

Orexin is a neuropeptide that modulates the energy and metabolism balance. The effects of orexin are mediated by one of the two G protein-coupled receptors, orexin receptor 1 or 2. OXRs are expressed in oxinergic projection areas of the brain and regulate food intake by reducing systemic and brain signals that drive over-eating. Synthetic peptide corresponding to the C-terminus of human orexin receptor 1, conjugated to KLH. The immunizing peptide has 70% homology with the rat and mouse gene.

Note

Protect from heat. Store away from oxidizing agents.

Letteratura

Kousaku Ohno.; Takeshi Sakurai. Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness. Frontiers in Neuroendocrinology. 2008, 29, (1), 70-87.

Katayama, S.; Hamasu, K.; Shigemi, K.; Cline, M.A.; Furuse, M. Intracerebroventricular injection of orexin-A, but not orexin-B, induces arousal of layer-type neonatal chicks. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2010, 157, (2), 132-135.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,6866
Codice tariffe armonizzato
2937.19
TSCA
No

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