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Lipoprotein, low density, oxidized, human plasma, Hi-TBAR, 99%, BT-910X - Hi-TBar-Ox-LDL - Oxidized LDL - J65261 - Alfa Aesar

J65261 Lipoprotein, low density, oxidized, human plasma, Hi-TBAR, 99%, BT-910X

Codice CAS
Sinonimi
Hi-TBar-Ox-LDL
Oxidized LDL

Dimensioni Prezzo ($) Quantità Disponibilità
2mg 223,00
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Lipoprotein, low density, oxidized, human plasma, Hi-TBAR, 99%, BT-910X

MDL
MFCD00131524

Proprietà chimiche

Modulo
Liquid

Applicazioni

Oxidized LDL induces foam cell formation in some macrophage cell lines. Research on foam cell formation is relevant to the study of atherosclerosis. Cellular exposure to ox-LDL results is the formation of lipid droplets containing cholesteryl esters in the cytoplasm of the macrophage as the lipoprotein particles are metabolized by the cell.Lipoprotein, low density, oxidized, human plasma, is used to induce foam cell formation in macrophages.

Note

TBARS: greater than equal to 45nmoles MDA/mg. Supplied at 1mg/ml in 1X phosphate-buffered saline, pH 7.4 and 0.3 mM EDTA. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 6 weeks.

Letteratura

Amézaga, N.;, Sanjurjo, L.; Julve, J.; Aran, G.; Pérez-Cabezas, B.; Bastos-Amador, P.; Armengol, C.; Vilella, R.; Escolà-Gil, J. C.; Blanco-Vaca, F.; Borràs, F. E.; Valledor, A. F.; Sarrias, M. R. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptakeJ Leukoc Biol 2014, 95 (3), 509-520.

Haller, E.; Lindner, W.; Lämmerhofer, M. Gold nanoparticle-antibody conjugates for specific extraction and subsequent analysis by liquid chromatography-tandem mass spectrometry of malondialdehyde-modified low density lipoprotein as biomarker for cardiovascular risk. Anal. Chim. Acta 2015, 857, 53-63.

Zhong, Q.; Zhao, S.; Yu, B.; Wang, X.; Matyal, R.; Li, Y.; Jiang, Z. High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARgamma/CD36 Pathway in Inflammatory Adipocytes. Int. J. Biol. Sci. 2015, 11 (3), 256-265.

Altri riferimenti

Codice tariffe armonizzato
2937.19
TSCA
No

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