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883973-99-7 - FBPase-1 Inhibitor - F16BPase Inhibitor - J65298 - Alfa Aesar

J65298 FBPase-1 Inhibitor

Codice CAS
883973-99-7
Sinonimi
F16BPase Inhibitor

Dimensioni Prezzo ($) Quantità Disponibilità
10mg 143,17
50mg 524,00
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FBPase-1 Inhibitor

MDL
MFCD22581250

Proprietà chimiche

Formula
C13H7Cl3N2O3S
Peso formula
377.60
Modulo
Solid
Sensibilità
Light Sensitive
Solubilità
Soluble in DMSO

Applicazioni

FBPase-1 Inhibitor that inhibits hFBPase-1 enzymatic activity by competing at the AMP allosteric binding site. FBPase-1 Inhibitor has been shown to block glucose production in starved rat hepatoma cells.

Note

Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Letteratura

Chunqiu Lai; Rebecca J. Gum; Melissa Daly; Elizabeth H. Fry; Charles Hutchins; Celerino Abad-Zapatero; Thomas W. von Geldern. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorganic & Medicinal Chemistry Letters. 2006, 16, (7), 1807-1810.

Thomas W. von Geldern; Chunqiu Lai; Rebecca J. Gum; Melissa Daly; Chaohong Sun; Elizabeth H. Fry; Celerino Abad-Zapatero. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorganic & Medicinal Chemistry Letters. 2006, 16, (7), 1811-1815.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
3504.00
TSCA
No

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