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J65298 FBPase-1 Inhibitor

Codice CAS
883973-99-7
Sinonimi
F16BPase Inhibitor

Stock No. Dimensioni Prezzo ($) Quantità Disponibilità
J65298-MA 10mg 133,00
J65298-MF 50mg 504,00
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FBPase-1 Inhibitor

MDL
MFCD22581250

Proprietà chimiche

Formula
C13H7Cl3N2O3S
Peso formula
377.60
Modulo
Solid
Storage & Sensitivity
Keep Cold. Light Sensitive.
Solubilità
Soluble in DMSO

Applicazioni

FBPase-1 Inhibitor that inhibits hFBPase-1 enzymatic activity by competing at the AMP allosteric binding site. FBPase-1 Inhibitor has been shown to block glucose production in starved rat hepatoma cells.

Note

Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Letteratura

Chunqiu Lai; Rebecca J. Gum; Melissa Daly; Elizabeth H. Fry; Charles Hutchins; Celerino Abad-Zapatero; Thomas W. von Geldern. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorganic & Medicinal Chemistry Letters. 2006, 16, (7), 1807-1810.

Thomas W. von Geldern; Chunqiu Lai; Rebecca J. Gum; Melissa Daly; Chaohong Sun; Elizabeth H. Fry; Celerino Abad-Zapatero. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorganic & Medicinal Chemistry Letters. 2006, 16, (7), 1811-1815.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
3504.00
TSCA
No

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