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Protease Inhibitor Cocktail VII, for His Tag Sequences, DMSO-Free - J65553 - Alfa Aesar

J65553 Protease Inhibitor Cocktail VII, for His Tag Sequences, DMSO-Free

Codice CAS
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1unit 110,21
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Protease Inhibitor Cocktail VII, for His Tag Sequences, DMSO-Free

Proprietà chimiche

Modulo
Lyophilized solid
Sensibilità
Hygroscopic
Solubilità
Insoluble in water.

Applicazioni

AEBSF and Aprotinin act to inhibit serine proteases, including trypsin, chymotrypsin, and plasmin amongst others. Bestatin inhibits aminpeptidases. E-64 acts against cystein proteases. Leupeptin acts against both serine and cystein proteases. Pepstatin A inhibits acid proteases.

Note

When reconstituted to 1ml, 1 unit makes a solution containing 100 mM AEBSF.HCl, 5mM bestatin, 1.5mM E-64, 2mM pepstatin A and 200uM phosphoramidon disodium salt

Letteratura

R B Kim; M F Fromm; C Wandel; B Leake; A J Wood; D M Roden; and G R Wilkinson. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest. 1998, 101, (2), 289-294.

David L. Paterson, MB, BS, FRACP; Susan Swindells, MD; Jeffrey Mohr, MSW; Michelle Brester, RN; Emanuel N. Vergis, MD; Cheryl Squier, RN; Marilyn M. Wagener, MPH; and Nina Singh, MD. Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection. Ann Intern Med. 2000, 133, (1), 21-30.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314

Causes severe skin burns and eye damage.

Dichiarazioni precauzionali: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Classe di rischio
8
Gruppo di imballaggio
III
Codice tariffe armonizzato
3822.00
TSCA
No

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