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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910 - Ox-LDL - Oxidized LDL - J65591 - Alfa Aesar

J65591 Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

Codice CAS
Sinonimi
Ox-LDL
Oxidized LDL

Dimensioni Prezzo ($) Quantità Disponibilità
2mg 223,00
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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

Proprietà chimiche

Modulo
Liquid

Applicazioni

Lipoprotein, low density, oxidized, human plasma, is evaluated for receptor binding to peritoneal macrophages. Furthermore, it is used to induce foam cell formation in macrophages.

Research on foam cell formation is relevant to the study of atherosclerosis. Cellular exposure to ox-LDL results in the formation of lipid droplets containing cholesteryl esters in the cytoplasm of the macrophage as the lipoprotein particles are metabolized by the cell.

Note

Supplied at 2mg/ml in 1X phosphate-buffered saline at pH 7.4 and 0.3 mM EDTA. Contains gentamicin sulfate. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 6 weeks. TBARS: 29-44 nmoles MDA/mg

Letteratura

Amezaga, N.; Sanjurjo, L.; Julve, J.; Aran, G.; Perez-Cebezas, B.; Bastos-Amador, P.; Armengol, C.; Vilella, R.; Escola-Gil, J. C.; Blanco-Vaca, F.; Borras, F. E.; Valledor, A. F.; Sarrias, M. -R. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake. J Leukoc Bio 2013, 95 (3), 509-520.

Zhang, Y.; Ye, Y.; Wang, Y.; Chen, W. Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia. Gynecol. Obstet. Invest. 2013, 79 (2), 90-96.

Zhang, Y.; Xie, Y.; You, S.; Han, Q.; Cao, Y.; Zhang, X.; Xiao, G.; Chen, R.; Liu, C. Autophagy and Apoptosis in the Response of Human Vascular Endothelial Cells to Oxidized Low-Density Lipoprotein. Cardiology 2015, 132 (1), 27-33.

Altri riferimenti

Codice tariffe armonizzato
2937.19
TSCA
No

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