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Oxaliplatin is an anti-tumor agent with activity against colorectal cancer. It shows antitumor activity in cell lines with acquired cisplatin resistance. It is used to treat cancer of the gullet (oesophagus). It is used as adjuvant therapy in patients who have had surgery to remove the cancer. It is used to treat testicular cancer.
D Khayat; M Gil-Delgado; E C Antoine; D Nizri; G Bastian. The role of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer. Oncology (Williston Park, N.Y.).2001, 15, (4), 414-415.
Peter Draxler; Silke Doris Honsek; Liesbeth Forsthuber; Viktoria Hadschieff; Jürgen Sandkühler. VGluT3? primary afferents play distinct roles in mechanical and cold hypersensitivity depending on pain etiology. Journal of Neuroscience.2014, 34, (36), 12015-12028.
Dichiarazioni di rischio (UE): H315-H319-H334-H317-H335
Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation.
Dichiarazioni precauzionali: P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.