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60-24-2 - 2-Mercaptoethanol, Electrophoresis Grade, 98+% - Thioethylene glycol - Thioglycol - J66742 - Alfa Aesar

J66742 2-Mercaptoethanol, Electrophoresis Grade, 98+%

Codice CAS
60-24-2
Sinonimi
Thioethylene glycol
Thioglycol

Dimensioni Prezzo ($) Quantità Disponibilità
250g 23,80
1000g 64,90
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2-Mercaptoethanol, Electrophoresis Grade, 98+%

MDL
MFCD00004890
EINECS
200-464-6

Proprietà chimiche

Formula
C2H6OS
Peso formula
78.13
Modulo
Liquid
Punto di fusione
-100°
Punto di ebollizione
156-158°
Punto di infiammabilità
73°(163°F)
Densità
1.114
Sensibilità
Air Sensitive & Hygroscopic
Solubilità
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.

Applicazioni

β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

Note

Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.

Letteratura

Margaret L. Heidrick..; Linda C. Hendricks.; David E. Cook. Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mechanisms of Ageing and Development. 1984, 27 (3),341-358 .

B. Tasheva.; G. Dessev. Artifacts in sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to 2-mercaptoethanol.Anal. Biochem. 1983, 129 (1),98-102 .

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H301-H310-H315-H317-H335-H318-H400-H410-H227

Toxic if swallowed. Fatal in contact with skin. Causes skin irritation. May cause an allergic skin reaction. May cause respiratory irritation. Causes serious eye damage. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects. Combustible liquid.

Dichiarazioni precauzionali: P210-P261-P262-P273-P301+P310-P305+P351+P338-P361-P302+P350-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Avoid release to the environment. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,5869
Beilstein
773648
Classe di rischio
6.1
Gruppo di imballaggio
II
Codice tariffe armonizzato
2930.90
TSCA
Yes
RTECS
KL5600000

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