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9041-93-4 - Bleomycin sulfate, Cell Culture Grade - J67560 - Alfa Aesar

J67560 Bleomycin sulfate, Cell Culture Grade

Codice CAS
9041-93-4
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
15mg 607,00
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Bleomycin sulfate, Cell Culture Grade

MDL
MFCD00070310
EINECS
232-925-2

Proprietà chimiche

Modulo
Powder
Solubilità
Soluble in water or DMSO

Applicazioni

Bleomycin sulfate binds to DNA, and can inhibit DNA synthesis and causes scission of DNA. Cleaves DNA, requires binding to oxygen and a metal ion, such as copper or iron. Able to cleave RNA, but at less and more selective degree. Also reported to induce and regulate apoptosis in a variety of cells, and inhibit tumor angiogenesis.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Letteratura

Walter B. Shelley, MD, PhD.; E. Dorinda Shelley, MD. Intralesional Bleomycin Sulfate Therapy for Warts A Novel Bifurcated Needle Puncture Technique. Arch Dermatol. 1991, 127 (2), 234-236.

R.J. Sollitto, DPM, FACFAS; David M. Pizzano, DPM. Bleomycin sulfate in the treatment of mosaic plantar verrucae: A follow-up study. The Journal of Foot and Ankle Surgery. 2010, 35 (2), 169-172.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H340-H351

May cause genetic defects. Suspected of causing cancer.

Dichiarazioni precauzionali: P201-P280-P202-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,1318
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
EC5991990

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