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4270-27-3 - 6-Chlorouracil, 98+% - 6-Chloro-2,4-dihydroxypyrimidine - 4-Chlorouracil - L01875 - Alfa Aesar

L01875 6-Chlorouracil, 98+%

Codice CAS
4270-27-3
Sinonimi
6-Chloro-2,4-dihydroxypyrimidine
4-Chlorouracil

Dimensioni Prezzo ($) Quantità Disponibilità
1g 45,00
5g 139,00
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6-Chlorouracil, 98+%

MDL
MFCD00014595
EINECS
224-258-0

Proprietà chimiche

Formula
C4H3ClN2O2
Peso formula
146.53
Punto di fusione
ca 295° dec.
Solubilità
Soluble in Ammonium Hydroxide

Applicazioni

Chlorouracil (4-Chlorouracil; 6-Chlorouracil) is a halogenated uracil that is useful in studies of the effects of halogenation on nucleic acid base-pair stability and alkali metal ion affinity. Reaction of 6-chlorouracil with 4-(dimethylamino)pyridine, 4-methylpyridine, and pyridin-4-yl-morpholine yielded pyridinium-substituted uracils as chlorides which were converted into pyridinium uracilates by deprotonation. These heterocyclic mesomeric betaines are cross-conjugated and thus possess separate cationic (pyridinium) and anionic (uracilate) moieties. Calculations and X-ray single crystal analyses may be used to characterize these systems and to compare the salts with the betaines.

Note

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Letteratura

Hongdeng Qiu.; Shengxiang Jiang.; Xia Liu. N-Methylimidazolium anion-exchange stationary phase for high-performance liquid chromatography. Journal of Chromatography A. 2006, 1103, (2), 265-270.

Troy Voelke.; Tim Ewell.; Jean Joo.; Eric D. Edstrom. o-Nitrobenzyl as a photocleavable nitrogen protecting group for indoles, benzimidazole, and 6-chlorouracil. Tetrahedron Letters. 1998, 39, (5-6), 359-362.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
120492
Codice tariffe armonizzato
2933.59
TSCA
No

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