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Indole-3-propionic acid is a reactant for preparation of fluorescent analogues of strigolactones, melanocortin receptors ligands, histamine H4 receptor agonists, and NR2B/NMDA receptor antagonists. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used to Study as an adjunct to improve perfusion after liver transplant.
Yuan-Hsiao Su et. al. Solution-phase parallel synthesis and screening of anti-tumor activities from fenbufen and ethacrynic acid libraries. Bioorganic & Medicinal Chemistry Letters.2011, 21,(5), 1320-1324 .
Francis Giraud et. al. Synthesis ofN-aryl-3-(indol-3-yl)propanamides and their immunosuppressive activities. Bioorganic & Medicinal Chemistry Letters.2011, 20,(17), 5203-5206.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.