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151-67-7 - 1-Bromo-1-chloro-2,2,2-trifluoroethane, 99% - 2-Bromo-2-chloro-1,1,1-trifluoroethane - Halothane - L10179 - Alfa Aesar

L10179 1-Bromo-1-chloro-2,2,2-trifluoroethane, 99%

Codice CAS
151-67-7
Sinonimi
2-Bromo-2-chloro-1,1,1-trifluoroethane
Halothane

Dimensioni Prezzo ($) Quantità Disponibilità
25g 37,29
100g 93,42
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1-Bromo-1-chloro-2,2,2-trifluoroethane, 99%

MDL
MFCD00009602
EINECS
205-796-5

Proprietà chimiche

Formula
CF3CHBrCl
Peso formula
197.39
Punto di ebollizione
49-50°
Densità
1.872
Indice di rifrazione
1.3691
Sensibilità
Light Sensitive
Solubilità
Soluble in water (8 mg/ml).

Applicazioni

1-Bromo-1-chloro-2,2,2-trifluoroethane has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. It is also used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.

Note

Light Sensitive. Store in the dark. Store away from oxidizing agents. Incompatible with light and oxidizing agents.

Letteratura

S Bourgoin; J P Ternaux; A Boireau; F Héry; M Hamon. Effects of halothane and nitrous oxide anesthesia on 5-HT turn-over in the rat brain.Naunyn-Schmiedebergs Archives of Pharmacology.1975, 288 (2-3), 109-121.

Travis J A Craddock; Marc St George; Holly Freedman; Khaled H Barakat; Sambasivarao Damaraju; Stuart Hameroff; Jack A Tuszynski. Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia.PLoS ONE.2012, 7 (6), e37251.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H318-H341

Causes serious eye damage. Suspected of causing genetic defects.

Dichiarazioni precauzionali: P201-P280-P281-P202-P305+P351+P338-P310-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4603
Beilstein
1736947
Codice tariffe armonizzato
2903.79
TSCA
No
RTECS
KH6550000

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