Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

3554-74-3 - 3-Hydroxy-1-methylpiperidine, 98% - 1-Methyl-3-piperidinol - L10829 - Alfa Aesar

L10829 3-Hydroxy-1-methylpiperidine, 98%

Codice CAS
3554-74-3
Sinonimi
1-Methyl-3-piperidinol

Dimensioni Prezzo ($) Quantità Disponibilità
5g 17,77
25g 59,40
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

3-Hydroxy-1-methylpiperidine, 98%

MDL
MFCD00006495
EINECS
222-609-2

Proprietà chimiche

Formula
C6H13NO
Peso formula
115.18
Punto di ebollizione
76-78°/11mm
Punto di infiammabilità
70°(158°F)
Densità
0.999
Indice di rifrazione
1.4740
Solubilità
Fully misicible in water.

Applicazioni

Reactant for Optimization of Novobiocin scaffold to produce antitumor agents, Formation of carbamates and N-alkylimidazoles. Reactant for synthesis of Pyridine derivatives as CDK5 inhibitors Phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors, Amino phosphite ligands, Mexiletine enantiomers by nucleophilic aromatic substitution.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Letteratura

Huiping Zhao et. al. Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.. Journal of medicinal and pharmaceutical chemistry,. 2007, 54 (11), 3839-3853.

Matthew R. Kaller et. al. Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (23), 6591-6594.

The Na derivative can be used in combination with Ni(OAc) 2 /NaH for desufurization of thioethers, showing dramatic rate enhancement compared with other systems: Tetrahedron Lett ., 39, 8987 (1998).

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Dichiarazioni precauzionali: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
103017
Codice tariffe armonizzato
2933.39
TSCA
Yes

Raccomandato

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio