3,5-Dichloro-2-hydroxybenzenesulfonyl chloride is used in the synthesis of (1R,2R)-(+)-1,2-(3,3?,5,5?-tetrachloro-2,2?-dihydroxydibenzenesulfonamido)-1,2-diphenylethane1 and (1R,2R)-(+)- 1,2-(3,3?,5,5?-tetrachloro-2,2?-dihydroxydibenzenesulfonamido)cyclohexane. It was used as chromogenic system in one-step kinetic method for the determination of 5?-nucleotidase.
A Bertrand; J Buret. A one-step determination of serum 5'-nucleotidase using a centrifugal analyzer. Clinica Chimica Acta.1982, 119, (3), 275-284.
Cheng Guo; Jun Qiu; Xumu Zhang; Dawn Verdugo; Martin L. Larter; Ray Christie; Patrick Kenney; Patrick J. Walsh. Enantioselective addition of diethylzinc to benzaldehyde catalyzed by chiral titanate complexes with helical ligands. Tetrahedron.1997, 53, 4145-4158.
Reagent for peptide coupling with low racemization: Tetrahedron Lett., 35, 9561 (1994). See Appendix 6. Reaction is thought to proceed via an o-thioquinone S,S-dioxide, leading to a carboxylic sulfonic mixed anhydride which rearranges to an active ester:
Dichiarazioni di rischio (UE): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Dichiarazioni precauzionali: P260u-P201-P280i-P304+P340-P405-P501a
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.