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10111-08-7 - Imidazole-2-carboxaldehyde, 97% - 2-Formylimidazole - L13883 - Alfa Aesar

L13883 Imidazole-2-carboxaldehyde, 97%

Codice CAS
10111-08-7
Sinonimi
2-Formylimidazole

Dimensioni Prezzo ($) Quantità Disponibilità
5g 80,00
25g 292,00
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Imidazole-2-carboxaldehyde, 97%

MDL
MFCD00003544
EINECS
000-000-0

Proprietà chimiche

Formula
C4H4N2O
Peso formula
96.09
Punto di fusione
ca 205° dec.
Sensibilità
Air Sensitive
Solubilità
Soluble in water.

Applicazioni

Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines.

Note

Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Letteratura

Joseyphus, R. S.; Shiju, C.; Joseph, J.; Dhanaraj, C. J.; Arish, D. Synthesis and characterization of metal complexes of Schiff base ligand derived from imidazole-2-carboxaldehyde and 4-aminoantipyrine. Spectrochim. Acta, Part A 2014, 133, 149-155.

Tinel, L.; Dumas, S.; George, C. A time-resolved study of the multiphase chemistry of excited carbonyls: Imidazole-2-carboxaldehyde and halides. C. R. Chim. 2014, 17 (7), 801-807.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
4371302
Codice tariffe armonizzato
2912.49
TSCA
No

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