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4767-03-7 - 2,2-Bis(hydroxymethyl)propionic acid, 98+% - L14014 - Alfa Aesar

L14014 2,2-Bis(hydroxymethyl)propionic acid, 98+%

Codice CAS
4767-03-7
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
100g 27,80
500g 67,40
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2,2-Bis(hydroxymethyl)propionic acid, 98+%

MDL
MFCD00004199
EINECS
225-306-3

Proprietà chimiche

Formula
C5H10O4
Peso formula
134.13
Punto di fusione
187-191°
Sensibilità
Hygroscopic
Solubilità
Soluble in acetone (slightly), methanol, and water. Insoluble in benzene.

Applicazioni

2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the “click” azide-acetylene cycloaddition.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature.

Letteratura

Elizabeth R. Gillies.; Jean M.J. Fréchet. Dendrimers and dendritic polymers in drug delivery. Drug Discovery Today. 2005, 10 (1), 35-43.

Ihre H.; Hult A. Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid. Macromolecules. 1999, 31 (13), 4061-4068.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P260-P201-P280g-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,3253
Beilstein
1756385
Codice tariffe armonizzato
2918.19
TSCA
Yes

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