Autorizzo l’utilizzo di cookies.

Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato

63148-57-2 - Poly(methylhydrosiloxane) - Methyl hydrogen polysiloxane - PMHS - L14561 - Alfa Aesar

L14561 Poly(methylhydrosiloxane)

Codice CAS
Methyl hydrogen polysiloxane

Dimensioni Prezzo ($) Quantità Disponibilità
50g 24,50
250g 43,40
1000g 142,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo



Proprietà chimiche

Peso formula
ca 1900
Punto di infiammabilità
Indice di rifrazione
Not miscible or difficult to mix in water.


Poly(methylhydrosiloxane) is used in the reduction of esters to alcohols, catalyzed by a combination of titanocene dichloride and either n-BuLi or EtMgBr. It is a safer alternative to triethoxysilane, B22063, for reduction of phosphine oxides to phosphines, catalyzed by Ti(O-i-Pr)4. It is also used in greener amine synthesis by reductive amination as an alternative to borohydrides.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with strong oxidizing agents, amines and bases.


Bhanu P. S. Chauhan.; Rajesh Sardar. Self-Assembled Stable Silver Nanoclusters and Nanonecklace Formation:? Poly(methylhydrosiloxane)-Mediated One-Pot Route to Organosols. Macromolecules. 2004, 37 (14), 5136-5139.

Bhanu P.S. Chauhan.; Philip Boudjouk. New neutral carrier-type ion sensors. Crown ether derivatives of poly(methylhydrosiloxane). Tetrahedron Letters. 1999, 40 (22), 4123-4126.

Convenient reducing agent with a wide variety of applications, for example:

Reduction of esters to alcohols, catalyzed by a combination of titanocene dichloride and either n-BuLi or EtMgBr: J. Org. Chem., 59, 4323 (1994). Alternatively, in combination with Ti(O-i-Pr)4 reduces a variety of esters, generally in high yield: J. Org. Chem., 60, 7884 (1995); Synlett, 831 (1994). For one-step reductive amination of carbonyl compounds in similar fashion, see: Synlett, 1655 (2000). Reduction of esters, carboxylic acids, ketones and aldehydes can also be accomplished conveniently with TBAF as a catalyst: Synlett, 989 (1997). For asymmetric reduction of ketones catalyzed by chiral quaternary fluorides, see: Tetrahedron Lett., 38, 5857 (1997).

Low-cost, safer alternative to Triethoxysilane, B22063, for reduction of phosphine oxides to phosphines, catalyzed by Ti(O-i-Pr)4. The products may be reacted in situ with alkyl halides to give a convenient one-pot conversion of phosphine oxides to phosphonium salts: Tetrahedron Lett., 35, 625 (1994).

Amine N-oxides can be reduced in the presence of Ti(O-i-Pr)4 or Pd(0): Synlett, 349 (2002).

Pd(0)-catalyzed hydrogenolysis of alkyl and aryl halides: J. Org. Chem., 51, 734 (1986). Pd(0)-catalyzed reductive cyclization of 1,6- and 1,7-enynes to give exomethylene cyclopentanes and cyclohexanes: J. Am. Chem. Soc., 109, 3161 (1987).

Low-cost alternative to Triethyl­silane, A10320, in a one-pot aromatic acylation-reduction technique allowing alkylation of the aromatic ring without the polysubstitution and rearrangements associated with Friedel-Crafts alkylations. Acylation in the presence of AlCl3 is followed by in situ reduction with PMHS: J. Chem. Soc., Perkin 1, 1705 (1989).

For a review of PMHS, see: J. Chem. Soc., Perkin 1, 3381 (1999).

Altri riferimenti

Codice tariffe armonizzato


Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali


Apparecchiature di analisi e di laboratorio