Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

50-91-9 - 5-Fluoro-2'-deoxyuridine, 98+% - 2'-Deoxy-5-fluorouridine - Floxuridine - L16497 - Alfa Aesar

L16497 5-Fluoro-2'-deoxyuridine, 98+%

Codice CAS
50-91-9
Sinonimi
2'-Deoxy-5-fluorouridine
Floxuridine

Dimensioni Prezzo ($) Quantità Disponibilità
100mg 79,21
500mg 261,62
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

5-Fluoro-2'-deoxyuridine, 98+%

MDL
MFCD00006530
EINECS
200-072-5

Proprietà chimiche

Formula
C9H11FN2O5
Peso formula
246.20
Punto di fusione
148-151°
Solubilità
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Applicazioni

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

Note

Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Letteratura

Rooney, J. P.; Luz, A. L.; Gonzalez-Hunt, C. P.; Bodhicharla, R.; Ryde, I. T.; Anbalagan, C.; Meyer, J. N. Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. Exp. Gerontol. 2014, 56, 69-76.

Kruspe, S.; Hahn, U. An Aptamer Intrinsically Comprising 5-Fluoro-2'-deoxyuridine for Targeted Chemotherapy. Mol. BioSyst. 2014, 53 (39), 10541-10544.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H360-H341-H302

May damage fertility or the unborn child. Suspected of causing genetic defects. Harmful if swallowed.

Dichiarazioni precauzionali: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4112
Beilstein
2645818
Classe di rischio
6.1
Gruppo di imballaggio
III
Codice tariffe armonizzato
2934.99
TSCA
No
RTECS
YU7535000

Raccomandato

  • A10926

    Diethylenetriaminepentaacetic acid, 98+%
  • A11079

    Sodium butyrate, 98+%
  • A12075

    Cacodylic acid, 98%
  • 11287

    Gadolinium(III) chloride hexahydrate, REacton®, 99.99% (REO)
  • 14248

    Iodine, crystalline, 99.5%

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio