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It is a reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, reactant for preparation of indole linked triazole derivatives as antifungal agents, reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes, reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents, reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors, reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents. 6-Methylindole was used in the synthesis of benz[c,d]indol-3(1H)-one derivatives.
H. R. Snyder.; Frederick J. Pilgrim. A Synthesis of 6-Methylindole and dl-6-Methyltryptophan.J. Am. Chem. Soc. 1948, 70 (11),3787-3788 .
Urs Hengartner.; Donald ValentineJr.; Katharine K. Johnson.; Mary Ellen Larscheid.; Foster Pigott.; Franz Scheidl.; John W. Scott.; Ruen C. Sun.; John M. Townsend.Synthesis of (R)-6-methyltryptophan via enantioselective catalytic hydrogenation. J. Org. Chem. 1979, 44 (22),3741-3747 .