(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone serves as a building block in the synthesis of (R)- and (S)-diaminovaleric acids1 and of 5-azasemicorrin bidentate nitrogen ligands for enantioselective catalysis.
Richard B. Silverman.; Mark A. Levy. Syntheses of (S)-5-substituted 4-aminopentanoic acids: a new class of .gamma.-aminobutyric acid transaminase inactivators. J. Org. Chem. 1980, 45 (5), 815-818.
John K. Thottathil, Jerome L. Moniot, Richard H. Mueller, Michael K. Y. Wong, Thomas P. Kissick. Conversion of L-pyroglutamic acid to 4-alkyl-substituted L-prolines. The synthesis of trans-4-cyclohexyl-L-proline. J. Org. Chem. 1986, 51 (16), 3140-3143.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.