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1006-41-3 - 2-Bromo-4-fluorobenzoic acid, 98% - L19321 - Alfa Aesar

L19321 2-Bromo-4-fluorobenzoic acid, 98%

Codice CAS
1006-41-3
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 21,22
5g 45,36
25g 150,38
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2-Bromo-4-fluorobenzoic acid, 98%

MDL
MFCD00055370
EINECS
000-000-0

Proprietà chimiche

Formula
C7H4BrFO2
Peso formula
219.01
Punto di fusione
167-169°
Solubilità
Soluble in water and methanol.

Applicazioni

2-Bromo-4-fluorobenzoic acid is used in the synthesis of 3-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-fluoro-8-(methylthio)dibenzo[b,f]thiepin-10(11H)-one, 2-((2-carboxy-5-fluorophenyl)amino)-3-methoxybenzoic acid and 2-bromo-4-fluorobenzamide. It is also used in the preparation of boron-containing anti-fungal agents, in the treatment of onychomycosis.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

Letteratura

Lauren R Donaldson.; Stephen Wallace.; David Haigh.; E Elizabeth Patton.; Alison N Hulme. Rapid synthesis and zebrafish evaluation of a phenanthridine-based small molecule library. Organic & Biomolecular Chemistry. 2011, 9 (7), 2233-2239.

Christian Wolf.; Shuanglong Liu.; Xuefeng Mei.; Adam T August.; Michael D Casimir. Regioselective copper-catalyzed amination of bromobenzoic acids using aliphatic and aromatic amines. Journal of Organic Chemistry. 2006, 71 (8), 3270-3273.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2614292
Codice tariffe armonizzato
2916.39
TSCA
No

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