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130-95-0 - Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine - A10459 - Alfa Aesar

A10459 Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine

CAS 번호
130-95-0
동의어

사이즈 가격 ($) 수량 재고 여부
10g 51.40
50g 170.00
250g 670.00
장바구니에 추가 대량 견적에 추가 항목 보기

Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine

MDL
MFCD00198096
EINECS
205-003-2

화학적 특성

화학식
C20H24N2O2
화학 식량
324.42
융점
ca 177° dec.
감도
Light Sensitive
용해도
Soluble in alcohol, chloroform and diethyl ether. Slightly soluble in water and glycerol.

용도

Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for the ligands used in sharpless asymmetric dihydroxylation. Furthermore, it catalyzes the kinetic resolution of furanones.

참고

Incompatible with strong oxidizing agents.

참조 문헌

Porta, R.; Benaglia, M.; Coccia, F.; Rossi, S.; Puglisi, A. Enantioselective Organocatalysis in Microreactors: Continuous Flow Synthesis of a (S)-Pregabalin Precursor and (S)-Warfarin. Symmetry 2015, 7 (3), 1395-1409.

Porta, R.; Coccia, F.; Annunziata, R.; Puglisi, A. Comparison of Different Polymer-and Silica-Supported 9-Amino-9-deoxy-epi-quinines as Recyclable Organocatalysts. ChemCatChem 2015, 7 (9), 1490-1499.

Kessler, S.; González, J.; Vlimant, M.; Glauser, G.; Guerin, P. M. Quinine and artesunate inhibit feeding in the African malaria mosquito Anopheles gambiae: the role of gustatory organs within the mouthparts. Physiol. Entomol. 2014, 39 (2), 172-182.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H334-H317-H335

Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation.

주의 설명서: P284-P261-P280a-P305+P351+P338-P405-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,8061
바일슈타인
91867
통합 관세 코드
2939.20
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
VA6020000

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