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88-67-5 - 2-Iodobenzoic acid, 98+% - A10563 - Alfa Aesar

A10563 2-Iodobenzoic acid, 98+%

CAS 번호
88-67-5
동의어

사이즈 가격 ($) 수량 재고 여부
25g 19.60
100g 57.60
500g 252.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Iodobenzoic acid, 98+%

MDL
MFCD00002419
EINECS
201-850-7

화학적 특성

화학식
C7H5IO2
화학 식량
248.02
융점
160-164°
밀도
2.250
감도
Light Sensitive
용해도
Soluble in dimethyl sulfoxide and methanol

용도

Reagent for detection of sulfhydryl groups in proteins2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.

참고

Incompatible with oxidizing agents.

참조 문헌

Can be used to protect alcohols as their 2-iodobenzoates by DCC coupling. The group is removed by oxidation with chlorine under basic conditions: Tetrahedron Lett., 28, 5005 (1987).

In the presence of Tetrakis(triphenyl­phosphine)­palladium(0)­, 10548 , and zinc chloride, undergoes cyclization with terminal acetylenes to give isocoumarins: J. Org. Chem., 60, 3711 (1995):

For related reactions, see 4,4-Dimethyl-2-pentyne, L10210 , 2-Iodoaniline, A13059 and 2-Iodophenol, A13599 .

Dang, Y.; Qu, S.; Nelson, J. W.; Pham, H. D.; Wang, Z. X.; Wang, X. The Mechanism of a Ligand-Promoted C(sp3)-H Activation and Arylation Reaction via Palladium Catalysis: Theoretical Demonstration of a Pd(II)/Pd(IV) Redox Manifold. J. Am. Chem. Soc. 2015, 137 (5), 2006-2014.

Yoshimura, A.; Nguyen, K. C.; Klasen, S. C.; Saito, A.; Nemykin, V. N.; Zhdankin, V. V. Preparation, structure, and versatile reactivity of pseudocyclic benziodoxole triflate, new hypervalent iodine reagent. Chem. Commun. 2015, 51 (37), 7835-7838.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,5030
바일슈타인
1861406
통합 관세 코드
2916.39
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
DH2975000

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