Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

623-00-7 - 4-Bromobenzonitrile, 98+% - 4-Cyanobromobenzene - A10914 - Alfa Aesar

A10914 4-Bromobenzonitrile, 98+%

CAS 번호
623-00-7
동의어
4-Cyanobromobenzene

사이즈 가격 ($) 수량 재고 여부
10g 39.40
50g 147.00
250g 548.00
장바구니에 추가 대량 견적에 추가 항목 보기

4-Bromobenzonitrile, 98+%

MDL
MFCD00001811
EINECS
210-764-9

화학적 특성

화학식
C7H4BrN
화학 식량
182.03
융점
111-114°
비등점
235-237°
인화점
130°(266°F)
밀도
1.562
용해도
Very slightly soluble in water(0.2g/L). Soluble in alcohol and ether.

용도

4-Bromobenzonitrile is used as reagents and solvents. Reaction of 2-propanol, 4-bromobenzonitrile, and NaH in the presence of 1.5 mol % Pd2(dba)3 and 3 mol % (S)-(-)2,2?-bis(di-p-tolylphosphino)- 1,1?-binaphthyl at 50°C afforded 4-isopropoxy- benzonitrile in 80% isolated yield. The synthesis of 4-cyanobiphenyl at room temperature in a flow injection microreactor, using a supported catalyst, without the addition of a base gave a product yield of 67±7% (n=6). This was achieved by injecting 4-bromobenzonitrile. The 3-arylation of 2,5-dimethylthiophene with 4-bromopropiophenone, 4-trifluoromethylbromobenzene or 4-bromobenzonitrile gave 3-5 in only 38-50% yields in Palladium-catalysed direct 3-or 4-arylation of thiophene derivatives using aryl bromides.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

참조 문헌

Michael Palucki,; John P. Wolf,; Stephen L. Buchwald. Palladium-Catalyzed Intermolecular Carbon-Oxygen Bond Formation:? A New Synthesis of Aryl Ethers. J. Am. Chem. Soc. 1997, 119 (14), 3395-3396.

Gillian M Greenway,; Stephen J Haswell,; David O Morgan,; Victoria Skelton,; Peter Styring. The use of a novel microreactor for high throughput continuous flow organic synthesis. Sensors and Actuators B: Chemical. 2000, (3) ,153-158.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H301-H312-H331-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
2041518
위험 등급
6.1
포장 그룹
III
통합 관세 코드
2926.90
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
DI2460000

권장

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품