I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
N,N'-Dicyclohexylcarbodiimide is a carboxyl activating reagent used in peptide synthesis. It acts as a dehydrating agent for the preparation of amides, ketones and nitriles. It is involved in the preparation of esters by reacting tertiary alcohols with carboxylic acid. It is utilized for the stereo chemical inversion of secondary alcohols by forming formyl ester followed by saponification. It is associated with dimethyl sulfoxide and used in Pfitzner-Moffatt oxidation to convert alcohols into aldehydes and ketones.
Blbulyan, S.; Trchounian, A. Impact of membrane-associated hydrogenases on the F O F 1-ATPase in Escherichia coli during glycerol and mixed carbon fermentation: ATPase activity and its inhibition by N, N'-dicyclohexylcarbodiimide in the mutants lacking hydrogenases. Arch. Biochem. Biophys. 2015, 579, 67-72.
Chen, J.; Zhang, J.; Zhang, W.; Chen, Z. Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N, N'-dicyclohexylcarbodiimide derivatization. J. Sep. Sci. 2014, 37 (1-2), 14-19.
해저드 설명서 (EU): H302-H311-H318-H317
Harmful if swallowed. Toxic in contact with skin. Causes serious eye damage. May cause an allergic skin reaction.
주의 설명서: P261-P280-P305+P351+P338-P310a-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.