A11324 Bromoacetaldehyde dimethyl acetal, 97+%, stab. with potassium carbonate
SDS
Bromoacetaldehyde dimethyl acetal, 97+%, stab. with potassium carbonate
화학적 특성
용도
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) was used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization.
참고
참조 문헌
Zunyi Yanga,; Hongzhi Caoa,; Jie Hua,; Renli Shanb;, Biao Yua. 1?2 Migration and concurrent glycosidation of phenyl 1-thio-α-mannopyranosides via 2, 3-O-cyclic dioxonium intermediates.. Tetrahedron. 2003, 59 (2), 249-254.
Chunyan Bao,; Ming Jin,; Bo Li,; Yaodong Xu,; Jingyan Jin,; Linyong Zhu. Long conjugated 2-nitrobenzyl derivative caged anticancer prodrugs with visible light regulated release: preparation and functionalizations. title . Org. Biomol. Chem.. 2012, 10 (27), 5238-5244.
GHS 해저드 및 주의 설명서
해저드 설명서 (EU): H226-H301-H330-H315-H319-H335
Flammable liquid and vapour. Toxic if swallowed. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P280h-P305+P351+P338-P309-P310a
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor
