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56-05-3 - 2-Amino-4,6-dichloropyrimidine, 98% - 4,6-Dichloro-2-pyrimidinamine - A11330 - Alfa Aesar

A11330 2-Amino-4,6-dichloropyrimidine, 98%

CAS 번호
56-05-3
동의어
4,6-Dichloro-2-pyrimidinamine

사이즈 가격 ($) 수량 재고 여부
5g 43.20
25g 137.00
100g 432.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Amino-4,6-dichloropyrimidine, 98%

MDL
MFCD00006090
EINECS
200-253-9

화학적 특성

화학식
C4H3Cl2N3
화학 식량
164.00
융점
218-222°
용해도
Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.

용도

Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

참조 문헌

Dana Hocková,; Antonı?n Holý,; Milena Masojı?dková,; Ivan Votruba. An efficient synthesis of cytostatic mono and bis-alkynylpyrimidine derivatives by the Sonogashira cross-coupling reactions of 2,4-diamino-6-iodopyrimidine and 2-amino-4,6-dichloropyrimidine. Tetrahedron. 2004, 60 (23), 4983-4987.

C. J. B. Clews,; W. Cochran. The structures of pyrimidines and purines. I. A determination of the structures of 2-amino-4-methyl-6-chloropyrimidine and 2-amino-4,6-dichloropyrimidine by X-ray methods . Acta Cryst.. 1948, 14-11.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
118454
통합 관세 코드
2933.59
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
UV6260485

권장

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