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40615-36-9 - 4,4'-Dimethoxytrityl chloride, 98% - 4,4'-Dimethoxytriphenylmethyl chloride - DMT - A11626 - Alfa Aesar

A11626 4,4'-Dimethoxytrityl chloride, 98%

CAS 번호
40615-36-9
동의어
4,4'-Dimethoxytriphenylmethyl chloride
DMT

사이즈 가격 ($) 수량 재고 여부
5g 43.10
25g 130.00
100g 460.00
장바구니에 추가 대량 견적에 추가 항목 보기

4,4'-Dimethoxytrityl chloride, 98%

MDL
MFCD00008409
EINECS
255-002-6

화학적 특성

화학식
C21H19ClO2
화학 식량
338.83
융점
121-127°
감도
Moisture Sensitive
용해도
Soluble in chloroform and methanol. Partially soluble in water

용도

4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.

참고

Moisture sensitive, hygroscopic. Incompatible with strong oxidizing agents.

참조 문헌

Ingale, S. A.; Leonard, P.; Tran, Q. N.; Seela, F. Duplex DNA and DNA-RNA Hybrids with Parallel Strand Orientation: 2'-Deoxy-2'-fluoroisocytidine, 2'-Deoxy-2'-fluoroisoguanosine, and Canonical Nucleosides with 2'-Fluoro Substituents Cause Unexpected Changes on the Double Helix Stability. J. Org. Chem. 2015, 80 (6), 3124-3138.

Vemekar, S. K. V.; Qiu, L.; Zhang, J.; Kankanala, J.; Li, H.; Geraghty, R. J.; Wang, Z. 5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus. J. Med. Chem. 2015, 58 (9), 4016-4028.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
2471942
통합 관세 코드
2909.30
TSCA(독성물질규제법)"
No

권장

  • A11493

    Thymidine, 99%
  • A11799

    Chlorotriphenylmethane, 98%
  • A12449

    1,8-Diazabicyclo[5.4.0]undec-7-ene, 99%
  • A12535

    Trimethylsilyl trifluoromethanesulfonate, 99%
  • 10548

    Tetrakis(triphenylphosphine)palladium(0), 99.8% (metals basis), Pd 9% min

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화학물질

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