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Ethyl 2-methylacetoacetate is used in Japp-Klingemann reaction to prepare hydrazones from beta-keto acid and aryl diazonium salts. It is used as a precursor involved in the synthesis of ethylpyruvate phenylhydrazone via reaction with benzenediazonium chloride.
Kula, S.; Szlapa, A.; Malecki, J. G.; Maron, A.; Matussek, M.; Balcerzak, E. S.; Siwy, M.; Domanski, M.; Sojka, M.; Danikiewicz, W.; Krompiec, S.; Filapek, M. Synthesis and photophysical properties of novel multisubstituted benzene and naphthalene derivatives with high 2D-pi-conjugation. Opt. Mater. 2015, 47, 118-128.
Hatamur, M.; Yamaguchi, S.; Takane, S.; Chen, Y.; Suganuma, K. Decarboxylation and simultaneous reduction of silver(I) beta-ketocarboxylates with three. Dalton Trans. 2015, 44 (19), 8993-9003.
해저드 설명서 (EU): H227
주의 설명서: P210u-P280a-P370+P378a-P403+P235-P501a
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