Diethylamine is used as a corrosion inhibitor. It is also used in the production of rubber, resins, dyes and pharmaceuticals. It is also used to cook lysergic acid diethylamide (LSD) and is strictly watched by Drug Enforcement Administration (DEA).
Alkali metal diethylamides, generated with n-BuLi or NaH, have been used for the cleavage of ethers: J. Organomet. Chem., 55, 41 (1973); Synthesis, 638 (1980), and of alkyl aryl sulfides, for which HBr and HI are usually poor: Synthesis, 583 (1982).
In combination with Lithium aluminum hydride, A18116, generates lithium tris(diethylamino)aluminum hydride, which is a useful selective reducing agent, for example: esters to aldehydes: J. Org. Chem., 52, 5486 (1987); amides to aldehydes: Tetrahedron Lett., 32, 6903 (1991).
Wang, N. N.; Zhang, D. L.; Jiang, X. H. Detection of Xeljanz Enantiomers in Diethyl Amine Active Pharmaceutical Ingredients and Tablets. Chirality 2015, 27 (3), 235-238.
Higashino, T.; Soya, T.; Kim, W.; Kim, D.; Osuka, A. A Mobius Aromatic Hexaphyrin Bearing a Diethylamine Group: A Rigid but Smooth Conjugation Circuit. Angew. Chem. Int. Ed. 2015, 54 (18), 5456-5459.
해저드 설명서 (EU): H225-H302-H312-H332-H314
Highly flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes severe skin burns and eye damage.
주의 설명서: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.