Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

110-86-1 - Pyridine, 99+% - A12005 - Alfa Aesar

A12005 Pyridine, 99+%

CAS 번호
110-86-1
동의어

사이즈 가격 ($) 수량 재고 여부
500ml 35.90
2500ml 115.00
10000ml 401.00
장바구니에 추가 대량 견적에 추가 항목 보기

Pyridine, 99+%

MDL
MFCD00011732
EINECS
203-809-9

화학적 특성

화학식
C5H5N
화학 식량
79.10
융점
-42°
비등점
115°
인화점
20°(68°F)
밀도
0.978
굴절률
1.5100
용해도
Miscible with water, alcohol, ether, pet ether, and oils.

용도

As polar, basic, low-reactive solvent, precursor, and reagent, pyridine finds wide range of applications in pharmaceuticals, agrochemicals and in the manufacture of dyes and rubber. Further it is used in the textile industry to improve network capacity of cotton. Pyridine finds applications in specialty chemical reagents like Cornforth reagent (pyridinium dichromate, PDC), pyridinium chlorochromate (PCC), the Collins reagent (complex of chromium(VI) oxide with pyridine) and the Sarret reagent (complex of chromium(VI) oxide with pyridine). Pyridine is a widely used ligand in coordination chemistry. Pyridine-base adducts like pyridine-borane and pyridine-sulfur trioxide are widely used owing to their superior characteristics in their reactivity and solubility characteristics.

참고

Pyridine is stable under normal temperatures and pressures. It is incompatible with strong oxidizing agents, and acids.

참조 문헌

Baumann, M.; Baxendale I. R. An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles. Beilstein J. Org. Chem. 2013, 9, 2265-2319.

Bull, J. A.; Mousseau, J. J.; Pelletier, G.; Charette, A. B. Synthesis of pyridine and dihydropyridine derivatives by regio- and stereoselective addition to N-activated pyridines. Chem. Rev. 2012, 112 (5), 2642-2713.

Widely used as a base and nucleophilic catalyst in acylations, sulfonylations, etc. See also 4-(Dimethyl­amino)­pyridine, A13016.

Reacts with thionyl chloride to give N-(4-pyridyl)pyridinium chloride hydrochloride, a useful intermediate for the preparation of 4-substituted pyridines by nucleophilic displacement. Thus, reaction with sulfite ion gives the sulfonate: Org. Synth. Coll., 5, 977 (1973). Similarly, pyridine can be activated to substitution at the 4-position by reaction with Ethyl­ chloroformate, L06311, or tert-Butyl­dimethyl­silyl­ trifluoromethanesulfonate, A12174. The acyl or silyl pyridinium salt then reacts with Grignards or organocuprates, to give 4-substituted dihydropyridines which can readily be rearomatized: Bull. Chem. Soc. Jpn., 57, 1994 (1984).

For use in Cr(VI) oxidation reactions, see Chromium(VI)­ oxide, 12522.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H225-H302-H312-H332

Highly flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

주의 설명서: P210-P261-P280-P303+P361+P353-P304+P340-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,7970
바일슈타인
103233
위험 등급
3
포장 그룹
II
통합 관세 코드
2933.31
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
UR8400000

권장

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품