Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

932-90-1 - Benzaldoxime, predominantly (E)-isomer, 98% - Benzaldehyde oxime - A12053 - Alfa Aesar

A12053 Benzaldoxime, predominantly (E)-isomer, 98%

CAS 번호
932-90-1
동의어
Benzaldehyde oxime

사이즈 가격 ($) 수량 재고 여부
25g 42.10
100g 123.00
500g 511.00
장바구니에 추가 대량 견적에 추가 항목 보기

Benzaldoxime, predominantly (E)-isomer, 98%

MDL
MFCD00002119
EINECS
213-261-2

화학적 특성

화학식
C7H7NO
화학 식량
121.14
융점
33-35°
비등점
118-120°/10mm
인화점
108°(226°F)
밀도
1.110
굴절률
1.5900
용해도
Slightly soluble in water. Soluble in ethanol and ether.

용도

Oximes are used as a peel-preventing additive in paints and lacquers. It acts as an antioxidant against oxidative drying materials which forms sticky skin with air oxygen. Oximes are used as chemical building block for the synthesis of agrochemicals and pharmaceuticals. In medicine application, Oxime structure is effective in cholinesterase reactivators to treat the poisoning by organophosphates. Oxime is used as a ligand in transition-metal complex catalyst chemistry. Oxime acts as an antioxidant, radical scavenger which find applications in textile, plastic, paint, detergent, and rubber industry.

참고

Store in cool place. Keep away from oxidizing agents. Incompatible with bases, acids, acid anhydrides and acid chlorides.

참조 문헌

Eberhard Buehler. Alkylation of syn- and anti-benzaldoximes. J. Org. Chem. 1967, 32 (2),261-265.

Jakob P Ley.; Heinz-Jürgen Bertram. Hydroxy- or Methoxy-Substituted Benzaldoximes and Benzaldehyde-O-alkyloximes as Tyrosinase Inhibitors.Bioorg. Med. Chem. 2001, 9 (7),1879-1885.

The oximate anion displaces activated aromatic nitro (or halogen) substituents. A second mole of oximate functions as base with elimination of benzonitrile and overall conversion of the nitro-compound to a phenol: J. Org. Chem., 39, 3343 (1974):

Conjugate addition of the oximate anion to ɑß-unsaturated acetylenic carbonyl compounds gives ß-dicarbonyl compounds: J. Org. Chem., 59, 1219 (1994). For example with reaction scheme, see Methyl­ phenyl­propiolate, B24587.

Aldoximes are conventionally dehydrated to nitriles with acetic anhydride; see, e.g.: Org. Synth. Coll., 2, 622 (1943). Many other dehydration methods have been described, including: Triethyl orthoformate and acid: J. Org. Chem., 39, 3424 (1974). DMF - SOCl2: Tetrahedron Lett., 25, 3365 (1984). SOCl2 - DMAP: Synthesis, 472 (1983). DCC: Synth. Commun., 3, 101 (1973); Chem. Ber., 107, 1221 (1974). PPh3 - CBr4: Synth. Commun., 20, 2785 (1990). Trichloromethyl chloroformate (diphosgene): Synthesis, 129 (1990). For a further example, see Trichloroacetonitrile, A10565. See also Hydroxyl­amine hydrochloride, A15398 for one-pot conversion of aldehydes to nitriles.

Chlorination followed by elimination of HCl from the benzohydroxamoyl chloride leads, in situ, to the 1,3-dipole benzonitrile oxide. See, e.g.: Org. Synth. Coll., 5, 504 (1973).

For conversion to the isothiocyanate, see Thiourea, A12828.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
774138
통합 관세 코드
2928.00
TSCA(독성물질규제법)"
Yes

권장

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품