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76-05-1 - Trifluoroacetic acid, 99% - Perfluoroacetic acid - A12198 - Alfa Aesar

A12198 Trifluoroacetic acid, 99%

CAS 번호
76-05-1
동의어
Perfluoroacetic acid

사이즈 가격 ($) 수량 재고 여부
100g 37.30
500g 115.00
2500g 459.00
장바구니에 추가 대량 견적에 추가 항목 보기

Trifluoroacetic acid, 99%

MDL
MFCD00004169
EINECS
200-929-3

화학적 특성

화학식
CF3CO2H
화학 식량
114.02
융점
-15°
비등점
72-73°
밀도
1.480
굴절률
1.2840
감도
Hygroscopic
용해도
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl<sub>4</sub>

용도

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

참고

Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

참조 문헌

López, S. E.; Salazar, J. Trifluoroacetic acid: Uses and recent applications in organic synthesis. J. Fluorine Chem. 2013, 156, 73-100.

Natu, A. D.; Burde, A. S.; Limaye, R. A.; Paradkar, M. V. Acceleration of the Dakin reaction by trifluoroacetic acid. J. Chem. Res. 2014, 38 (6), 325-386.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H332-H314

Harmful if inhaled. Causes severe skin burns and eye damage.

주의 설명서: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,9681
바일슈타인
742035
위험 등급
8
포장 그룹
I
통합 관세 코드
2915.90
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
AJ9625000

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