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504-24-5 - 4-Aminopyridine, 98% - Fampridine - 4-Pyridinamine - A12405 - Alfa Aesar

A12405 4-Aminopyridine, 98%

CAS 번호
504-24-5
동의어
Fampridine
4-Pyridinamine

사이즈 가격 ($) 수량 재고 여부
50g 52.70
250g 212.00
1000g 722.00
장바구니에 추가 대량 견적에 추가 항목 보기

4-Aminopyridine, 98%

MDL
MFCD00006439
EINECS
207-987-9

화학적 특성

화학식
C5H6N2
화학 식량
94.12
융점
157-161°
비등점
273-274°
인화점
164°(327°F)
밀도
1.26
용해도
Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.

용도

It is used as a research tool, in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis. In the laboratory, 4-AP is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. Spinal cord injury patients have also seen improvement with 4-AP therapy.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

참조 문헌

H Bostock et. al.The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres. Journal of Physiology. 1981, 313 301-315.

Shun-ichi Yamaguchi,; Michael A. Rogawski.Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice . Epilepsy Research. 1992, 11(1), 9-16.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H300-H311-H315-H319-H335

Fatal if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P273-P280h-P270-P301+P310a-P305+P351+P338-P302+P352a

Avoid release to the environment. Wear protective gloves/clothing. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON SKIN: Wash with plenty of water.

기타 참조

Merck
14,3933
바일슈타인
105782
위험 등급
6.1
포장 그룹
II
통합 관세 코드
2933.39
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
US1750000

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