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91-56-5 - Isatin, 98% - 2,3-Indolinedione - A12468 - Alfa Aesar

A12468 Isatin, 98%

CAS 번호
91-56-5
동의어
2,3-Indolinedione

사이즈 가격 ($) 수량 재고 여부
100g 21.00
500g 74.50
2500g 292.00
장바구니에 추가 대량 견적에 추가 항목 보기

Isatin, 98%

MDL
MFCD00005718
EINECS
202-077-8

화학적 특성

화학식
C8H5NO2
화학 식량
147.13
융점
ca 199-200°
인화점
220°(428°F)
용해도
Soluble in water (1.9 g/L at 20°C).

용도

Isatin is an endogenous monoamine oxidize (MAO) inhibitor involved in stress and anxiety. Additionally, isatin inhibits alkaline phosphatase (ALP), nitric oxide (NO)-stimulated soluble guanylate cyclase, and other enzymes. Isatins undergo a one-pot Wolff-Kishner like reduction with hydrazine hydrate, under surprisingly mild conditions, to give the corresponding oxindoles. It is used as chromatographic spray reagent for amino acid detection.

참고

Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.

참조 문헌

Seshaiah Krishnan Sridhar.; Surendra N Pandey.; James P Stables.; Atmakuru Ramesh. Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives. European Journal of Pharmaceutical Sciences. 2002, 16 (3),129-132.

S.N. Pandeya.; D. Sriram.; G. Nath.; E. DeClercq. Synthesis, antibacterial, antifungal and anti-HIV activities of Schiff and Mannich bases derived from isatin derivatives and N-[4-(4?-chlorophenyl)thiazol-2-yl] thiosemicarbazide. European Journal of Pharmaceutical Sciences. 1999, 9 (1),25-31.

Isatins undergo a one-pot Wolff-Kishner like reduction with hydrazine hydrate, under surprisingly mild conditions, to give the corresponding oxindoles: Synth. Commun., 24, 2835 (1994).

Reaction with acid anhydrides or condensation with 4-Methyl-2-pentanone, A11618, results in the formation of quinoline-4-carboxylic acid derivatives; for examples, see: J. Med. Chem., 35, 4893 (1992); 36, 617, 3286 (1993).:

기타 참조

Merck
14,5104
바일슈타인
383659
통합 관세 코드
2933.79
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
NL7873000

권장

최근에 본 것

화학물질

화학물질

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