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3,4-(Methylenedioxy)aniline is an pharmaceutically important aniline derivative. It undergoes N-alkylation with cyclic secondary alkylamines in the presence of Shvo catalyst to yield N-arylpyrrolidines. 3,4-(Methylenedioxy)aniline was used in the synthesis of γ-glutamylanilides.
SJ Tu.; XD Cao.; WJ Hao.; XH Zhang .; S Yan. An efficient and chemoselective synthesis of benzo [e][1, 4] thiazepin-2 (1 H, 3 H, 5 H)-ones via a microwave-assisted multi-component reaction in water. Organic & Biomolecular Chemistry. 20097, (3) , 557-563.
MJ Luzzio.; JM Besterman.; DL Emerson. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J. Med. Chem. 199538, (3) , 395-401.
해저드 설명서 (EU): H302-H312-H331-H315-H319
Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation.
주의 설명서: P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.