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Esters derived from trans-4-methoxycinnamic acid are effective absorbers of UV radiation. The starting material was trans-4-methoxycinnamic acid and 3,5dimethoxybenzoic acid methyl ester in isolated avenanthramide alkaloids synthsis. trans-4-Methoxycinnamic acid was converted into its acid chloride (yield 98%) with thionyl chloride. Employed in organic synthesis of pharmaceutical intermediates, synthetic anti-adrenergic drugs esmolol, cosmetics ultraviolet absorption.
Anton Blaakmeer,; Dick van der Wal,; André Stork,; Teris A. van Beek,; Aede de Groot,; Joop J. A. van Loon. Structure-Activity Relationship of Isolated Avenanthramide Alkaloids and Synthesized Related Compounds as Oviposition Deterrents for Pieris brassicae . J. Nat. Prod., . 1994, 57 (8), 1145-1151.
Ryan G. Stabile,; Andrew P. Dicks. Two-Step Semi-Microscale Preparation of a Cinnamate Ester Sunscreen Analog. J. Chem. Educ. 2004, 81 (10), 1488.
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.