Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

2344-80-1 - (Chloromethyl)trimethylsilane, 98% - A14303 - Alfa Aesar

A14303 (Chloromethyl)trimethylsilane, 98%

CAS 번호
2344-80-1
동의어

사이즈 가격 ($) 수량 재고 여부
10g 42.40
50g 126.00
250g 551.00
장바구니에 추가 대량 견적에 추가 항목 보기

(Chloromethyl)trimethylsilane, 98%

MDL
MFCD00000878
EINECS
219-058-5

화학적 특성

화학식
ClCH2Si(CH3)3
화학 식량
122.67
비등점
97-98°
인화점
-2°(28°F)
밀도
0.886
굴절률
1.4180
감도
Moisture Sensitive
용해도
Soluble in water (0.4g/L at 20°C).

용도

(Chloromethyl)trimethylsilane is used for Wittig reaction and building blocks.

참고

Store in cool, well ventilated area. Keep container tightly closed. Moisture sensitive. Store under argon.

참조 문헌

Akira Sekiguchi; Wataru Ando. Direct synthesis of terminal olefins from ketones. Application of (chloromethyl)trimethylsilane to a Wittig reaction. J. Org. Chem. 1979, 44 (3), 413-415.

John W. Connolly; Grant Urry. The Wurtz Reaction of Chloromethyltrimethylsilane. A Classical Study. J. Org. Chem. 1964, 29 (3), 619-623.

Treatment with s-BuLi at -78o gives ɑ-lithio-ɑ-chloromethyltrimethylsilane which reacts with aldehydes and ketones to give ɑß-epoxy silanes, readily hydrolyzed to homologated aldehydes: Tetrahedron, 39, 867 (1983):

Metallation gives useful precursors of various organosilicon compounds. For use of the Grignard in the olefination of ketones, see: J. Org. Chem., 39, 3264 (1974); 52, 281 (1987). For Ni-catalyzed reaction of the Grignard with allylic dithioacetals, see: J. Org. Chem., 53, 5582 (1988); Org. Synth. Coll., 9, 727 (1998); for an example with reaction scheme, see trans-Cinnamaldehyde, A14689.

For a review of the chemistry of chloromethyltrimethylsilane, see: Synthesis, 717 (1985).

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H225-H315-H319-H335

Highly flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
906705
위험 등급
3
포장 그룹
II
통합 관세 코드
2931.90
TSCA(독성물질규제법)"
Yes

권장

  • A10616

    1,3-Diiodopropane, 98+%, stab. with copper
  • A11125

    Cyclopropanecarbonitrile, 98%
  • A12124

    Diphenylphosphonic azide, 97%
  • A14899

    (Chloromethyl)dimethylchlorosilane, 98%
  • B22188

    2-Chloro-4'-fluoroacetophenone, 99%

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품