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76-05-1 - Trifluoroacetic acid, biochemical grade, 99.5+% - A14365 - Alfa Aesar

A14365 Trifluoroacetic acid, biochemical grade, 99.5+%

CAS 번호
76-05-1
동의어

사이즈 가격 ($) 수량 재고 여부
50g 43.00
250g 114.00
1000g 355.00
장바구니에 추가 대량 견적에 추가 항목 보기

Trifluoroacetic acid, biochemical grade, 99.5+%

MDL
MFCD00004169
EINECS
200-929-3

화학적 특성

화학식
CF3CO2H
화학 식량
114.02
융점
-15°
비등점
72-73°
밀도
1.480
굴절률
1.2840
감도
Hygroscopic
용해도
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.

용도

Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

참고

Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

참조 문헌

López, S. E.; Salazar, J. Trifluoroacetic acid: Uses and recent applications in organic synthesis. J. Fluorine Chem. 2013, 156, 73-100.

Natu, A. D.; Burde, A. S.; Limaye, R. A.; Paradkar, M. V. Acceleration of the Dakin reaction by trifluoroacetic acid. J. Chem. Res. 2014, 38 (6), 325-386.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H332-H314

Harmful if inhaled. Causes severe skin burns and eye damage.

주의 설명서: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,9681
바일슈타인
742035
위험 등급
8
포장 그룹
I
통합 관세 코드
2915.90
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
AJ9625000

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