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497-25-6 - 2-Oxazolidinone, 99% - 2-Oxazolidone - A14543 - Alfa Aesar

A14543 2-Oxazolidinone, 99%

CAS 번호
497-25-6
동의어
2-Oxazolidone

사이즈 가격 ($) 수량 재고 여부
25g 38.70
100g 107.00
500g 364.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Oxazolidinone, 99%

MDL
MFCD00005268
EINECS
207-840-9

화학적 특성

화학식
C3H5NO2
화학 식량
87.08
융점
84-89°
비등점
220°/48mm
용해도
Soluble in water.

용도

2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.

참고

Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.

참조 문헌

Hideaki Kakeya; Masayuki Morishita; Hiroyuki Koshino; Tetsu-ichiro Morita; Kimiko Kobayashi and Hiroyuki Osada. Cytoxazone:? A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp. J. Org. Chem. 1999, 64 (3), 1052-1053.

Guo-Jie Ho; David J. Mathre. Lithium-Initiated Imide Formation. A Simple Method for N-Acylation of 2-Oxazolidinones and Bornane-2,10-Sultam. J. Org. Chem. 1995, 60 (7), 2271-2273.

Has been used as an ethanolamine equivalent, e.g. in reaction with succinic anhydride to give 1-(2-hydroxyethyl)succinimide: Tetrahedron, 44, 261 (1988). Also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives: J. Org. Chem., 57, 6257 (1992).

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
106251
통합 관세 코드
2934.99
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
RQ2450000

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