Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

62637-93-8 - Trimethylamine N-oxide dihydrate, 98+% - A14916 - Alfa Aesar

A14916 Trimethylamine N-oxide dihydrate, 98+%

CAS 번호
62637-93-8
동의어

사이즈 가격 ($) 수량 재고 여부
5g 30.00
25g 45.40
100g 111.00
500g 441.00
장바구니에 추가 대량 견적에 추가 항목 보기

Trimethylamine N-oxide dihydrate, 98+%

MDL
MFCD00149077

화학적 특성

화학식
(CH3)3NO•2H2O
화학 식량
111.14 (75.11anhy)
융점
96-101°
용해도
Soluble in water, ethanol, dimethyl sulfoxide and methanol. Sparingly soluble in hot chloroform. Insoluble in diethyl ether, benzene and hydrocarbon solvents.

용도

Trimethylamine N-oxide dihydrate is used as an oxidizing agent in organic synthesis. It is also used to make quaternary ammonium compounds and a warning agent for flammable gas. Further, it acts as a flavoring agent or adjuvant. It serves as an oxidant for the catalytic osmium tetraoxide cis-hydroxylation of hindered olefins. In addition to this, it is used as a reactant for C-H bond cleavage and decarbonylating agent for solvent-free reactions.

참고

Hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

참조 문헌

Reagent for the liberation of organics from their complexes with iron carbonyls. Partial oxidation of CO to CO2 takes place: J. Chem. Soc., Chem. Commun., 336 (1974).

Also oxidizes alkylboranes to alcohols, giving less interference with other functionality than the more usual H2O2: J. Org. Chem., 40, 1776 (1975).

Has been used in the oxidation of alkyl halides to aldehydes. For a procedure, including dehydration of the N-oxide by distillation of water with DMF, see: Org. Synth. Coll., 5, 872 (1973):

For an improved procedure using DMSO, see: Tetrahedron Lett., 31, 4825 (1990).

For use as a reoxidant in the catalytic cis-hydroxylation of alkenes with Osmium(VIII)­ oxide, 12103 , see: Tetrahedron Lett., 21, 449 (1980).

Deprotonation by LDA at low temperature gives the unstable azomethine ylide, which undergoes 1,3-dipolar addition, even with unactivated alkenes, to give pyrrolidines: J. Chem. Soc., Chem. Commun., 31 (1983):

Reviews: Trimethylamine as a useful oxidizing agent: J. Prakt. Chem./ Chem. Ztg., 338, 190 (1996); The utility of N-oxides in synthesis: Synthesis, 263 (1993).

Compare also 4-Methyl­morpholine N-oxide monohydrate, A15996 .

Hunger, J.; Ottosson, N.; Mazur, K.; Bonn, M.; Bakker, H. J. Water-mediated interactions between trimethylamine-N-oxide and urea. Phys. Chem. Chem. Phys. 2015, 17 (1), 298-306.

Makarov, D. M.; Egorov, G. I.; Kolker, A. M. Density and Volumetric Properties of Aqueous Solutions of Trimethylamine N-Oxide in the Temperature Range from (278.15 to 323.15) K and at Pressures up to 100 MPa. J. Chem. Eng. Data 2015, 60 (5), 1291-1299.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

주의 설명서: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313

Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists:

기타 참조

Merck
14,9710
바일슈타인
3612927
통합 관세 코드
2922.50
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
YH2850000

권장

  • A14547

    p-Toluenesulfonyl chloride, 98%
  • A15806

    Nitrosonium tetrafluoroborate, 98%
  • A19802

    4-Methylmorpholine N-oxide, 50% w/w aq. soln.
  • L09658

    Tetramethylammonium hydroxide pentahydrate, 98%
  • L13174

    Benzoyl peroxide, 97% (dry wt.), wet with 25% water

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품