4-Hydroxychalcone is used as anti-angiogenesis, antineoplastic. It is also used as organic intermediates.
O.A. Oyedapo; C.O. Adewunmi; E.O. Iwalewa and V.O. Makanju. Analgesic, Antioxidant and Anti-inflammatory Related Activities of 21-hydroxy-2,41-dimethoxychalcone and 4-hydroxychalcone in Mice.Journal of Biological Sciences.2008, 8 131-136.
Barbora Orlikovaa; Deniz Tasdemirb; Frantisek Golaisc; Mario Dicatoa; Marc Diedericha. The aromatic ketone 4?-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition.Biochemical Pharmacology.2011, 82 620-631.
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.