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569-58-4 - Aluminon - Aurintricarboxylic acid triammonium salt - A15401 - Alfa Aesar

A15401 Aluminon

CAS 번호
569-58-4
동의어
Aurintricarboxylic acid triammonium salt

사이즈 가격 ($) 수량 재고 여부
10g 23.70
50g 59.70
250g 249.00
장바구니에 추가 대량 견적에 추가 항목 보기

Aluminon

MDL
MFCD00040925
EINECS
209-319-1

화학적 특성

화학식
C22H23N3O9
화학 식량
473.44
융점
220-225° dec.
용해도
Soluble in water(800g/L).

용도

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

참조 문헌

R G González,; R S Haxo,; T Schleich. Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein--nucleic acid interactions. Biochemistry (Washington). 1980, 19 (18),4299-4303.

Y Benchokroun,; J Couprie,; A K Larsen. Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells. Biochemical Pharmacology. 1995, 49(3), 305-313.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

주의 설명서: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313

Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists:

기타 참조

Merck
14,322
통합 관세 코드
2918.99
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
GU4800000

권장

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    Lead(II) nitrate, 99%
  • 00010

    Aluminum powder, -40+325 mesh, 99.8% (metals basis)

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