It is a building block used for the synthesis of various compounds, having therapeutic properties, such as synthesis of 4-Benzimidazolyl-piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists.
Laura C. Cooper, et al. 2-Aryl Indole NK1 receptor antagonists: optimisation of indole substitution.Bioorg. Med. Chem. Lett.,2009,11(9), 1233-1236.
Duncan Shawa, et al. 2-Aryl indole NK1 antagonists: optimisation of the amide substituent.Bioorg. Med. Chem. Lett.,2001,11(23), 3031-3034.
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.