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5455-59-4 - 2-Nitrobenzenesulfonamide, 98+% - A15689 - Alfa Aesar

A15689 2-Nitrobenzenesulfonamide, 98+%

CAS 번호
5455-59-4
동의어

사이즈 가격 ($) 수량 재고 여부
5g 50.80
10g 82.70
25g 170.00
100g 503.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Nitrobenzenesulfonamide, 98+%

MDL
MFCD00009807
EINECS
000-000-0

화학적 특성

화학식
C6H6N2O4S
화학 식량
202.19
융점
188-194°
용해도
Slightly soluble in water.

용도

It is applied as a reagent for synthesis of medium-ring amines via N-alkylation, e.g. with ω-bromo alkanols under Mitsunobu conditions (DEAD/PPh3), and cyclization of the resulting ω-bromo alkylsulfonamides (Cs2CO3/Bu4NI). It is a carbonic anhydrase inhibitor. It is employed as a reactant involved in synthesis of cyclic nitrogen compounds via intramolecular hydroamination, pentacyclic lycopodium alkaloid huperzine-Q2, pyrrolidines, intermolecular C-H insertion reactions and reactant involved in intermolecular amination of allyl alcohols.

참고

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

참조 문헌

Atsushi Nakayama, et al. Asymmetric total synthesis of a pentacyclic Lycopodium alkaloid: huperzine-Q.Angew Chem Int Ed Engl.,2011,50(35), 8025-8028.

Hideto Ito, et al. Intramolecular hydroamination of alkynic sulfonamides catalyzed by a gold-triethynylphosphine complex: Construction of azepine frameworks by 7-exo-dig cyclization.Beilstein J Org Chem.,2011,7951-959.

Reagent for synthesis of medium-ring amines via N-alkylation, e.g. with ω-bromo alkanols under Mitsunobu conditions (DEAD/PPh3), and cyclization of the resulting ω-bromo alkylsulfonamides (Cs2CO3/Bu4NI): Synlett, 697 (2002) and references therein. See also 2-Nitrobenzenesulfonyl­ chloride, B21522.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
2214215
통합 관세 코드
2935.90
TSCA(독성물질규제법)"
No

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