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88-10-8 - Diethylcarbamyl chloride, 98% - N,N-Diethylcarbamoyl chloride - N,N-Diethylchloroformamide - A15701 - Alfa Aesar

A15701 Diethylcarbamyl chloride, 98%

CAS 번호
88-10-8
동의어
N,N-Diethylcarbamoyl chloride
N,N-Diethylchloroformamide

사이즈 가격 ($) 수량 재고 여부
25g 15.20
100g 46.60
장바구니에 추가 대량 견적에 추가 항목 보기

Diethylcarbamyl chloride, 98%

MDL
MFCD00000636
EINECS
201-798-5

화학적 특성

화학식
C5H10ClNO
화학 식량
135.59
융점
-32°
비등점
186°
인화점
76°(168°F)
밀도
1.070
굴절률
1.4510
감도
Moisture Sensitive
용해도
Reacts with water.

용도

It is used in the production of pharma ingredients. It is a reagent in the synthesis of S-Methyl-N,N-diethylthiocarbamate Sulfoxide, which is an oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase.

참고

Moisture sensitive. Store away from bases, water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep ignition sources away.

참조 문헌

A. Segal, et al. Formation of 6-dimethylcarbamyloxy-dGuo, 6-dimethylamino-dGuo and 4-dimethylamino-dThd following in vitro reaction of dimethylcarbamyl chloride with calf thymus DNA and 6-diethylcarbamyloxy-dGuo following in vitro reaction of diethylcarbamyl chloride with calf thymus DNA.Chem. Biol. Interact.,1982,40(2), 209-231.

S. Kushner, et al. Experimental chemotherapy of filariasis. v. the preparation of derivatives of piperazine.J. Org. Chem.,1948,13(1), 144-153.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H227-H302-H332-H315-H319-H351-H335

Combustible liquid. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. May cause respiratory irritation.

주의 설명서: P210u-P201-P261-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
506687
위험 등급
8
포장 그룹
II
통합 관세 코드
2924.19
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
FD4025000

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